autoantigen

Share on Facebook Share on Twitter Email
American Heritage Dictionary:

au·to·an·ti·gen

Top
(ô'tō-ăn'tĭ-jən) pronunciation
n.
An endogenous antigen that stimulates the production of autoantibodies, as in an autoimmune reaction.


(ô'tō-ăn'tĭ-jən)
n.

A tissue constituent that evokes an immune response to the host's tissues.


an antigen that is a normal constituent of an individual and has the capacity to produce an immune response in the same individual in certain circumstances. Examples include: thyroid peroxidase (in autoimmune thyroiditis); TSH receptor (in Graves' disease); skeletal muscle acetylcholine receptor (in myasthenia gravis); and myelin basic protein (in multiple sclerosis).

Previous:autoantibody, autoanalyser, autoallergy
Next:autocatalysis, autochthonous, autoclave

A tissue constituent that stimulates production of autoantibodies or self-reactive T lymphocytes in the animal in which it occurs.

Post a question - any question - to the WikiAnswers community:

Copyrights: