Azurophilic granule
American Heritage Stedman's Medical Dictionary:
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a·zu·ro·phil
(ă-zhʊr'ə-fĭl', ăzh'ə-rō-fĭl') or a·zu·ro·phile (-fīl', -fĭl')
adj.
adj.
Staining readily with an azure dye. Used especially in reference to certain cytoplasmic granules in white blood cells.
Saunders Veterinary Dictionary:
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azurophil
A tissue constituent staining with azure or a similar metachromatic thiazine dye.
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Azurophilic granule
| Azurophilic granule | |
|---|---|
| Latin | granulum azurophilum |
| Code | TH H2.00.04.1.02011 TH H2.00.04.1.02014 |
An azurophil is an object readily stained with an azure stain. in white blood cells and hyperchromatin, imparting a burgundy or merlot coloration. Neutrophils in particular are known for containing azurophils loaded with a wide variety of anti-microbial defensins that fuse with phagocytic vacuoles. Azurophils may contain myeloperoxidase, phospholipase A2, Acid Hydrolases, Elastase, defensins, neutral serine proteases, bactericidal/permeability-increasing protein, [1] lysozyme, cathepsin G, proteinase 3, and proteoglycans.
Azurophil granules are also known as "primary granules".[2]
See also
References
- ^ "Phagocytes-Neutrophils". http://www.dent.ucla.edu/pic/members/neutrophils/neutrophils2.html.
- ^ John P. Greer; Maxwell Myer Wintrobe (1 December 2008). Wintrobe's clinical hematology. Lippincott Williams & Wilkins. pp. 173–. ISBN 978-0-7817-6507-7. http://books.google.com/books?id=68enzUD7BVgC&pg=PA173. Retrieved 10 November 2010.
External links
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American Heritage Stedman's Medical Dictionary
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company.
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Saunders Veterinary Dictionary
Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved.
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