B-transferase
Oxford Dictionary of Biochemistry:
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B-transferase
EC 2.4.1.37; recommended name: fucosylglycoprotein 3-α-galactosyltransferase; other name: [histo-blood group] B transferase; an enzyme that catalyses the reaction:
UDPgalactose + glycoprotein α-l-fucosyl-(1,2)-d-galactose = UDP + glycoprotein α-d-galactosyl-(1,3)-[α-l-fucosyl-(1,2)]-l-galactose
, thus adding galactose to the H antigen of the ABH antigen system, leading to formation of the B antigen. The protein is a product of one allele of the ABO gene. It has virtual identity of sequence with that catalysing A-transferase activity, differing only at residues 176 (A has Arg, B has Gly), 235 (A Gly, B Ser), 266 (A Leu, B Met), and 268 (A Gly, B Ala).
| B-DNA, B side, B region | |
| B/F ratio, BAC, BACE2 |
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