Bemiparin sodium
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bemiparin sodium
A low molecular weight heparin used for the prevention and treatment of deep-vein thrombosis and for the prevention of blood clots in patients undergoing kidney dialysis. It is available as a solution for subcutaneous injection on prescription only.
Side effects, precautions, and interactions with other drugs:
see heparin.
Proprietary preparation:
Zibor.
| belladonna extract, beclometasone dipropionate, becaplermin | |
| bendroflumethiazide, benperidol, benserazide hydrochloride |
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Bemiparin sodium
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Bemiparin sodium
| Clinical data | |
|---|---|
| AHFS/Drugs.com | International Drug Names |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 91449-79-5  |
| ATC code | B01AB12 |
| Chemical data | |
| Formula | ? |
| Mol. mass | 3600 Daltons (average) |
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Bemiparin is an antithrombotic and belongs to the group of low molecular weight heparins (LMWH).[1]
Like semuloparin, bemiparin is classified as an ultra-LMWH because of its low molecular mass of 3600 Daltons on average.[2] (Enoxaparin has 4500 Daltons.) These heparins have lower anti-thrombin activity than classical LMWHs and act mainly on factor Xa, reducing the risk of bleeding.[3]
References
- ^ Chapman TM, Goa KL (2003). "Bemiparin: a review of its use in the prevention of venous thromboembolism and treatment of deep vein thrombosis". Drugs 63 (21): 2357–77. PMID 14524738.
- ^ Planès, A. (2003). "Review of bemiparin sodium – a new second-generation low molecular weight heparinand its applications in venous thromboembolism". Expert Opinion on Pharmacotherapy 4 (9): 1551–1561. doi:10.1517/14656566.4.9.1551. PMID 12943485.
- ^ Jeske, W. P.; Hoppensteadt, D.; Gray, A.; Walenga, J. M.; Cunanan, J.; Myers, L.; Fareed, J.; Bayol, A. et al. (2011). "A common standard is inappropriate for determining the potency of ultra low molecular weight heparins such as semuloparin and bemiparin". Thrombosis Research 128 (4): 361–367. doi:10.1016/j.thromres.2011.03.001. PMID 21458847.
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