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Biapenem

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Biapenem
Systematic (IUPAC) name
(4R,5S,6S)-3-(6,7-dihydro-5H- pyrazolo[1,2-a][1,2,4]triazol-8- ium-6-ylsulfanyl)- 6-(1-hydroxyethyl)- 4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2- ene-2-carboxylate
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy cat.  ?
Legal status ℞ Prescription only
Routes IV
Identifiers
CAS number 120410-24-4
ATC code J01DH05
PubChem CID 71339
ChemSpider 64442 YesY
UNII YR5U3L9ZH1 YesY
ChEBI CHEBI:3089 YesY
ChEMBL CHEMBL285347 YesY
Chemical data
Formula C15H18N4O4S 
Mol. mass 350.39 g/mol
SMILES eMolecules & PubChem
 YesY(what is this?)  (verify)

Biapenem (INN) is a carbapenem antibiotic. It has in vitro activity against anaerobes.[1]

Approved in Japan in 2001.

References

  1. ^ Aldridge KE, Morice N, Schiro DD (April 1994). "In vitro activity of biapenem (L-627), a new carbapenem, against anaerobes". Antimicrob. Agents Chemother. 38 (4): 889–93. PMC 284564. PMID 8031067. http://aac.asm.org/cgi/pmidlookup?view=long&pmid=8031067. 

External links

v · d · eAntibacterials: cell envelope antibiotics (J01C-J01D)
Intracellular
inhibit peptidoglycan subunit synthesis and transport: NAM synthesis inhibition (Fosfomycin) • DADAL/AR inhibitors (Cycloserine) • bactoprenol inhibitors (Bacitracin)
Glycopeptide
inhibit PG chain elongation: Vancomycin# (Oritavancin, Telavancin) • Teicoplanin (Dalbavancin) • Ramoplanin
β-lactams/
(inhibit PBP
cross-links)
Biapenem • Ertapenem • antipseudomonal (Doripenem • Imipenem • Meropenem) • Panipenem
Combinations
Other
#WHO-EM. ‡Withdrawn from market. Clinical trials: †Phase III. §Never to phase III

M: BAC

drug(J1p, w, n, m, vacc)
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