Bombesin: Definition from Answers.com

Bombesin

Other names	Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
Identifiers
CAS number	31362-50-2
PubChem	16133891
Properties
Molecular formula	C₇₁H₁₁₀N₂₄O₁₈S
Molar mass	1619.85
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Bombesin is a 14-amino acid peptide originally isolated from the skin of a frog. It has two known homologs in mammals called neuromedin B and gastrin releasing peptide. It stimulates gastrin release from G cells. It activates three different G-protein-coupled receptors known as BBR1 2 & 3. It also activates these receptors in the brain. Together with cholecystokinin, it is the second major source of negative feedback signals that stop eating behaviour.

Bombesin is also a tumor marker for small cell carcinoma of lung, gastric cancer, and neuroblastoma.

v • d • e Peptides: neuropeptides

Hypothalamic	Somatostatin • CRH • GnRH • GHRH • Orexins • TRH • POMC (ACTH, MSH, Lipotropin)

Gastrointestinal hormones	Cholecystokinin • Gastric inhibitory polypeptide • Gastrin • Motilin • Secretin • Vasoactive intestinal peptide

Other hormones	Calcitonin • Oxytocin • Vasopressin

Other	Angiotensin • Bombesin • Calcitonin gene-related peptide • Carnosine • Cocaine and amphetamine regulated transcript • Delta sleep-inducing peptide • FMRFamide • Galanin • Galanin-like peptide • Gastrin releasing peptide • Kinins (Bradykinin, Tachykinins ) • Neuromedin (B, N, S, U) • Neuropeptide S • Neuropeptide Y • Neurophysins • Neurotensin • Opioid peptides (Dynorphin, Endomorphin, Endorphin, Enkephalin, Nociceptin, Opiorphin) • Pancreatic polypeptide • Pituitary adenylate cyclase activating peptide • VGF

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		Medical Dictionary. The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Read more
		Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved. Read more
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Bombesin