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Bucladesine
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| Systematic (IUPAC) name | |
| sodium (3aR,4R,6R,6aR)-4-(6-butanamido-9H-purin-9-yl)-6-[(butanoyloxy)methyl]-2-oxo-tetrahydro-2H-1,3,5,2λ5-furo[3,4-d][1,3,2]dioxaphosphol-2-olate | |
| Identifiers | |
| CAS number | 362-74-3 |
| ATC code | C01CE04 |
| PubChem | 28177 |
| Chemical data | |
| Formula | C18H23N5NaO8P |
| Mol. mass | 491.368 g/mol |
| Synonyms | • Dibutyryl cyclic adenosine monophosphate • (N6,2'-O-dibutyryl-adenosine-3',5'-mono-phosphate • Dibutyryl cAMP • DcAMP • DBcAMP |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | ? |
Bucladesine is a cyclic nucleotide derivative which mimics the action of endogenous cAMP and is a phosphodiesterase inhibitor.
Bucladesine is a cell permeable cAMP analog. The compound is used in a wide variety of research applications because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions. cAMP is only able to elicit minimal responses in these situations.
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