Dictionary:

calcinosis

  (kăl'sə-nō'sĭs)

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An abnormal condition in which calcium salts are deposited in a part or tissue of the body.

[CALC(I)– (influenced by CALCINE) + –OSIS.]

Abnormal deposition of calcium salts in tissues. May be due to excessive intake of vitamin D.

1. the deposition of calcium salts in various tissues because of hypercalcemia and tissue degeneration. 2. the presence of calcification in or under the skin. The condition may occur in a localized (calcinosis circumscripta) or generalized (calcinosis universalis) form.

A condition characterized by abnormal deposition of calcium salts in the tissues.

• c. circumscripta — localized deposition of calcium in small nodules in subcutaneous tissues, tongue or attached to tendons or joint capsules. Called also tumoral calcinosis.
• c. cutis — cutaneous mineralization, a characteristic lesion in dogs with hyperadrenocorticism. Lesions are commonest on the dorsal midline, ventral abdomen and inguinal region. The skin is usually thin and atrophic.

  Calcinosis cutis in a dog with Cushing's syndrome.

• enzootic c. — calcinosis occurring in larger numbers of animals in a local population than chance warrants. Usually a plant poisoning. May be caused by the following calcinogenic plants: solanum malacoxylon, S. linneanum, cestrum diurnum, nierembergia veitchii and trisetum flavescens. Manifested clinically by chronic wasting, reluctance to walk and constant shifting of weight from limb to limb. Called also enteque seco.
• multicentric periarticular c. — described in Hungarian vizsla dogs in association with a renal tubular defect in phosphorus transport, causing progressive lameness.
• pulmonary c. — see microlithiasis.
• tumoral c. — circumscribed, hard swellings with a granular radiopacity, usually immovable and located in horses on the lateral aspect of the proximal tibia.
• c. universalis — widespread deposition of calcium in nodules or plaques in the dermis, panniculus and muscles.

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