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calcium-channel blocker

 
Medical Encyclopedia: Calcium Channel Blockers
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Definition

Calcium channel blockers are medicines that slow the movement of calcium into the cells of the heart and blood vessels. This, in turn, relaxes blood vessels, increases the supply of oxygen-rich blood to the heart, and reduces the heart's workload.

Description

Calcium channel blockers are available only with a physician's prescription and are sold in tablet, capsule, and injectable forms. Some commonly used calcium channel blockers include amlopidine (Norvasc), diltiazem (Cardizem), isradipine (DynaCirc), nifedipine (Adalat, Procardia), nicardipine (Cardene), and vera-pamil (Calan, Isoptin, Verelan).

The recommended dosage depends on the type, strength, and form of calcium channel blocker and the condition for which it is prescribed. Correct dosage is determined by the prescribing physician and further information can be obtained from the pharmacist.

Calcium channel blockers should be taken as directed. Larger or more frequent doses should not be taken, nor should doses be missed. This medicine may take several weeks to noticeably lower blood pressure. The patient taking calcium channel blockers should keep taking the medicine, to give it time to work. Once it begins to work and symptoms improve, it should continue to be taken as prescribed.

This medicine should not be discontinued without checking with the prescribing physician. Some conditions may worsen when patients stop taking calcium channel blockers abruptly. The prescribing physician will advise as to how to gradually taper down before stopping the medication completely.

— Deanna M. Swartout-Corbeil, R.N.



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Dental Dictionary: calcium channel blocker
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n

A drug that inhibits the flow of calcium ions across the membranes of smooth muscle cells. The reduction of calcium flow relaxes smooth muscle tone and reduces the risk of muscle spasms. Calcium channel blockers are used in the prevention and treatment of coronary artery spasms.

 
Columbia Encyclopedia: calcium-channel blocker
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calcium-channel blocker, any of a class of drugs used in treating hypertension, angina pectoris, and certain arrhythmias. They prevent the calcium ions needed for muscle contraction from entering the cells of smooth and cardiac muscle. This causes blood vessel walls to relax and blood to flow more freely to the heart, lowering blood pressure and relieving anginal pain. Some calcium-channel blockers, such as Procardia (nifedipine), slow the electrical impulses that run through heart muscle, thus regulating arrhythmias. Cardizem (diltiazem) is a common calcium-channel blocker.


Veterinary Dictionary: calcium channel blocker
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A drug, such as nifedipine or verapamil, that selectively blocks the influx of calcium ions through a specific ion channel (the slow channel or calcium channel) of cardiac muscle and smooth muscle cells; used in the treatment of cardiac arrhythmias. Calcium channel blockers act to control arrhythmias by slowing the rate of sinoatrial (SA) node discharge and the conduction velocity through the atrioventricular (AV) node. Called also calcium blocker, calcium antagonist.

 
 

 

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Medical Encyclopedia. © 2006 through a partnership of Answers Corporation. All rights reserved.  Read more
Dental Dictionary. Mosby's Dental Dictionary. Copyright © 2004 by Elsevier, Inc. All rights reserved.  Read more
Columbia Encyclopedia. The Columbia Electronic Encyclopedia, Sixth Edition Copyright © 2003, Columbia University Press. Licensed from Columbia University Press. All rights reserved. www.cc.columbia.edu/cu/cup/ Read more
Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved.  Read more