Carbaminohemoglobin

Carbaminohemoglobin (or Carbaminohaemoglobin, also known as carbhemoglobin and carbohemoglobin) is a compound of hemoglobin and carbon dioxide, which is one of the forms in which carbon dioxide exists in the blood. Binding to carbon dioxide lowers hemoglobin's affinity for oxygen when carbaminohemoglobin is formed, via the Bohr Effect. When hemoglobin is not bound to oxygen, it has a higher tendency to become carbaminohemoglobin; this is known as the Haldane effect. Carbaminohemoglobin is blueish in color, so the veins, whose blood contains the compound, appears blue.^[1]

Binding of carbon dioxide in carbaminohemoglobin is not always agreed upon with certain biochemistry texts. Some texts suggest that 4 carbon dioxide molecules bind to hemoglobin. This binding does not occur at the same place as oxygen binding although 4 oxygen molecules do bind to hemoglobin. Other biochemistry texts suggest that carbon dioxide does not bind at all and is found only floating in the cytoplasm of the red blood cell. Further studies of this seemed contradiction are being conducted.

See also

• Hemoglobin
• Blood
• Carbamino

References

http://books.google.com/books?id=sKT2Sq4P0j8C&pg=PA431&lpg=PA431&dq=carbon+dioxide+does+not+bind+hemoglobin+at+the+same+site+as+oxygen&source=bl&ots=Y1Oi0bVbtB&sig=Jb6R_sJvGb5LtqB6jB0BXo_UmbA&hl=en&ei=08CNSqSkM6iRtgeI9rCCDg&sa=X&oi=book_result&ct=result&resnum=10#

External links

• carbaminohemoglobin at eMedicine Dictionary
• MeSH carbaminohemoglobin+A

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