| Carol Greider | |
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| Born | April 15, 1961 San Diego, California |
| Residence | United States of America |
| Nationality | American |
| Fields | Molecular biology |
| Institutions | Cold Spring Harbor Laboratory Johns Hopkins University |
| Alma mater | Davis Senior High School(1979) University of California, Santa Barbara(1983) University of California, Berkeley(1987) |
| Doctoral advisor | Elizabeth Blackburn |
| Known for | discovery of telomerase |
| Notable awards | Lasker Award, Louisa Gross Horwitz Prize, Nobel Prize for Physiology or Medicine (2009) |
Carolyn Widney "Carol" Greider[1][2] (born April 15, 1961) is a molecular biologist at the Johns Hopkins University. She was a co-discoverer of the enzyme telomerase in 1984 while working under Elizabeth Blackburn at the University of California, Berkeley. Greider pioneered research on the structure of telomeres, the ends of the chromosomes. She was awarded the 2009 Nobel Prize for Physiology or Medicine, along with Elizabeth Blackburn and Jack W. Szostak of Boston, Massachusetts, for their discovery of how telomeres are protected from progressive shortening by the enzyme telomerase.[3]
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Life and career
Greider is the Daniel Nathans Professor and the Director of Molecular Biology and Genetics at the Johns Hopkins Institute of Basic Biomedical Sciences.
Greider was born in San Diego, California.[4] Her father, Kenneth Greider, was a physics professor.[5] Her family moved from San Diego to Davis, California, where she spent many of her early years. She graduated from the College of Creative Studies at the University of California, Santa Barbara, with a B.A. in biology in 1983. During this time she also studied at the University of Göttingen and made significant discoveries there.[6] She completed her Ph.D. in molecular biology in 1987 at the University of California, Berkeley, under Elizabeth Blackburn. While at U.C. Berkeley, Greider co-discovered telomerase, a key enzyme in cancer and anemia research, along with Blackburn.
Greider then completed her postdoctoral work, and also held a faculty position, at the Cold Spring Harbor Laboratory, Long Island, New York. She next moved on to a faculty position at the Johns Hopkins University in 1997, where she remains employed.
She has two children: Charles, 13, and Gwendolyn, 10.
Awards and honors
- Gairdner Foundation International Award (1998)
- Member of the American Society for Cell Biology (1999)
- Member of the National Academy of Sciences (2003)
- The Richard Lounsbery Award (2003), National Academy of Sciences[7]
- The Dickson Prize (2006)
- The Wiley Prize in Biomedical Sciences (2006) (shared with Elizabeth Blackburn)
- The Lasker Award for Basic Medical Research (2006) (shared with Elizabeth Blackburn and Jack Szostak)
- The Louisa Gross Horwitz Prize (2007) (shared with Elizabeth Blackburn and Joseph G. Gall)
- Paul Ehrlich and Ludwig Darmstaedter Prize (2009) (shared with Elizabeth Blackburn)
- The Nobel Prize for Physiology or Medicine (2009) (shared with Elizabeth Blackburn and Jack Szostak)"[8]
Selected works
- Greider, C. W. & Blackburn, E. H. (1985), "Identification of a specific telomere terminal transferase activity in Tetrahymena extracts", Cell 43 (2 Pt. 1): 405–413
- Greider, C. W. & Blackburn, E. H. (1996), "Telomeres, Telomerase and Cancer", Scientific American: 92–97
See also
References
- ^ According to the State of California. California Birth Index, 1905-1995. Center for Health Statistics, California Department of Health Services, Sacramento, California. Searchable at http://www.familytreelegends.com/records/39461
- ^ http://www.britannica.com/EBchecked/topic/1567677/Greider-Carol-W
- ^ "Blackburn, Greider, and Szostak share Nobel". Dolan DNA Learning Center. http://blogs.dnalc.org/dnaftb/2009/10/05/blackburn-greider-and-szostak-share-nobel-for-telomeres/. Retrieved 2009-10-05.
- ^ Hopkins “Telomere” expert Carol Greider shares Germany's largest science prize
- ^ http://theaggie.org/article/former-davis-resident-receives-nobel-prize
- ^ Press release, University of Göttingen (9 Dec. 2009).
- ^ NAS Online ("For her pioneering biochemical and genetic studies of telomerase, the enzyme that maintains the ends of chromosomes in eukaryotic cells.")
- ^ "Nobel Prize in Physiology or Medicine 2009". Nobel Foundation. http://nobelprize.org/nobel_prizes/medicine/laureates/2009/. Retrieved 2009-10-05.
Further reading
External links
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