Caruncle (Latin: caruncula "wart") may refer to:
- In botany, an elaiosome (fleshy structure attached to the seed), especially in the plant family Euphorbiaceae
- In animal anatomy:
- prostomium, the sensory organ of Annelid worms
- the wattle (anatomy) or cockscomb of some birds
- In human anatomy:
- sublingual caruncle, an area on the tongue
- a small, red portion of the corner of the eye that contains modified sebaceous and sweat glands (See Ciaccio's glands)
- various small fleshy excrescences (normal or abnormal outgrowths)
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