CBB can be abbreviation for:
- Connexion by Boeing, a mobile ISP formerly offered by The Boeing Company.
- Central Bank of Barbados (CBB) See also: Barbados
- Circular barbell, a common design of body piercing jewelry
- Colby-Bates-Bowdoin, an athletic conference in Maine, USA
- Computational Biology and Bioinformatics
- Celebrity Big Brother
- An internet slang abbreviation for "can't be bothered" and "could be better".
- An abbreviation for Custom Built Backgammon
- Common Building Block, a set of standards for laptop components introduced by Intel, making it possible to take components from one CBB laptop into another possibly from a competing manufacturer.
- Coomassie brilliant blue, a blue dye commonly used to stain proteins in SDS-PAGE/BN-PAGE gels.
- Stock symbol on New York Stock Exchange for Cincinnati Bell.
- Converged Big Bang
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