n.
A broad-spectrum antibiotic, C22H23ClN2O8, obtained from the soil bacterium Streptomyces aureofaciens and used in the treatment of a variety of infections.
chlortetracycline
| Dictionary: chlor·tet·ra·cy·cline |
(klôr'tĕt-rə-sī'klēn', -klĭn, klōr'-)
n.
A broad-spectrum antibiotic, C22H23ClN2O8, obtained from the soil bacterium Streptomyces aureofaciens and used in the treatment of a variety of infections.
n.
A broad-spectrum antibiotic, C22H23ClN2O8, obtained from the soil bacterium Streptomyces aureofaciens and used in the treatment of a variety of infections.
| 5min Related Video: chlortetracycline |
| Dental Dictionary: chlortetracycline |
(klôr′tetrəsīklēn)
n
n
(Aureomycin) a broad-spectrum antibiotic possessing bacteriostatic properties of some value in the treatment of disease produced by large viruses (the psittacosis and lymphogranuloma inguinale groups).
| Veterinary Dictionary: chlortetracycline |
A broad-spectrum antibiotic obtained from Streptomyces aureofaciens, used in the form of the hydrochloride salt as an antibacterial (effective against both gram-positive and gram-negative bacteria) and as a feed additive to promote growth in calves, pigs and poultry. See also tetracycline.
| Wikipedia: Chlortetracycline |
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Chlortetracycline
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| Systematic (IUPAC) name | |
| (4S,4aS,5aS,6S,12aS,Z)-2-[amino(hydroxy)methylene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydrotetracene-1,3,12(2H,4H,12aH)-trione | |
| Identifiers | |
| CAS number | 57-62-5 |
| ATC code | A01AB21 D06 J01 S01 QJ51 |
| PubChem | 5280963 |
| ChemSpider | 10469370 |
| Chemical data | |
| Formula | C22H23ClN2O8 |
| Mol. mass | 478.88 g/mol |
| SMILES | eMolecules & PubChem |
| Pharmacokinetic data | |
| Bioavailability | 30% |
| Protein binding | 50 to 55% |
| Metabolism | Hepatic (75%) |
| Half life | 5.6 to 9 hours |
| Excretion | Renal and biliary |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | Oral, IV, topical |
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Chlortetracycline (trade name Aureomycin, Lederle) is a tetracycline antibiotic, and was the first tetracycline to be discovered. It was discovered in 1945 by Dr Benjamin Duggar in a soil sample from Sanborn Field at the University of Missouri, yielding an actinomycete, Streptomyces aureofaciens (hence the name Aureomycin). In veterinary medicine, it is commonly used to treat conjunctivitis in cats.[1]
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 | Aureomycin |
| Acronize |
| tetracycline |
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 | Dictionary. The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2009. Published by Houghton Mifflin Company. All rights reserved. Read more |
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| Dental Dictionary. Mosby's Dental Dictionary. Copyright © 2004 by Elsevier, Inc. All rights reserved. Read more |
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| Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved. Read more |
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| Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "Chlortetracycline". Read more |
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