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Chorionic Villus Sampling: Purpose

 
Medical Encyclopedia: Chorionic Villus Sampling: Purpose

Chorionic villus sampling is performed on pregnant women who are at risk for carrying a fetus with a genetic or chromosomal defect. Although it carries a slightly higher risk, CVS may be used in place of amniocentesis for women who have one or more of the following risk factors:

  • Women age 35 and older. The chance of having a child with Down syndrome increases with maternal age. For instance, the chance of having a baby with Down syndrome is one in 378 for a 35-year-old woman and increases to one in 30 for a 45-year-old woman.
  • A history of miscarriages or children born with birth defects.
  • A family history of genetic disease. Prenatal genetic testing is recommended if either the mother or father of the unborn baby has a family history of genetic disease or is known to be a carrier of a genetic disease.

— Belinda Rowland, PhD



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