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Chorionic Villus Sampling: Risks

 
Medical Encyclopedia: Chorionic Villus Sampling: Risks

Of women who undergo transcervical chorionic villus sampling, one third experience minimal vaginal spotting and 7–10% experience vaginal bleeding. One out of five women experience cramping following the procedure. Two to three women out of 100 (or 2–3%) will mis-carry following chorionic villus sampling. The risk of infection is very low. Rupture of the amniotic membranes is a rare complication. Women with Rh negative blood may be at an increased risk for developing Rh incompatibility following chorionic villus sampling.

There have been reports of limb defects in babies following chorionic villus sampling. However, in 1996 the World Health Organization reported that the incidence of babies born with limb defects from 138,966 women who had undergone chorionic villus sampling was the same as for women who had not. Therefore, this study found no connection between chorionic villus sampling and limb defects.

— Belinda Rowland, PhD



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