Climazolam


Climazolam
Systematic (IUPAC) name
8-chloro-6-(2-chlorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
Identifiers
CAS number	59467-77-5
ATC code	?
PubChem	68790
Chemical data
Formula	C₁₈H₁₃Cl₂N₃
Mol. mass	342.222
SMILES	eMolecules & PubChem
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Climazolam (Ro21-3982) is a drug which is an imidazo benzodiazepine derivative developed by Hoffman-LaRoche. It is similar in structure to triazolam, and is used in veterinary medicine for anaesthetising animals.^[1]^[2]

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References

^ Ganter M, Kanngiesser M. Effect of ketamine and its combinations with xylazine and climazolam on the circulation and respiration in swine. (German) Zentralblatt fur Veterinarmedizin. Reihe A. 1991 Aug;38(7):501-9. PMID 1950241
^ Bettschart-Wolfensberger R, Taylor PM, Sear JW, Bloomfield MR, Rentsch K, Dawling S. Physiologic effects of anesthesia induced and maintained by intravenous administration of a climazolam-ketamine combination in ponies premedicated with acepromazine and xylazine. American Journal of Veterinary Research. 1996 Oct;57(10):1472-7. PMID 8896687

v • d • e Benzodiazepines (N05BA, N05CD)

1,4-Benzodiazepines	Bromazepam • Camazepam • Chlordiazepoxide • Cinolazepam • Clonazepam • Clorazepate • Cyprazepam • Delorazepam • Diazepam • Doxefazepam • Elfazepam • Ethyl carfluzepate • Ethyl dirazepate • Ethyl loflazepate • Fletazepam • Fludiazepam • Flunitrazepam • Flurazepam • Flutemazepam • Flutoprazepam • Fosazepam • Gidazepam • Halazepam • Iclazepam • Lopirazepam • Lorazepam • Lormetazepam • Meclonazepam • Medazepam • Menitrazepam • Metaclazepam • Nimetazepam • Nitrazepam • Nitrazepate • Nordazepam • Oxazepam • Oxazepam hemisuccinate • Phenazepam • Pinazepam • Pivoxazepam • Prazepam • Proflazepam • Quazepam • QH-II-66 • Reclazepam • Sulazepam • Temazepam • Tetrazepam • Uldazepam

1,5-Benzodiazepines	Arfendazam • Clobazam • Lofendazam • Triflubazam • Zomebazam

2,3-Benzodiazepines	Girisopam • GYKI-52895 • Nerisopam • Tofisopam

Triazolobenzodiazepines	Adinazolam • Alprazolam • Estazolam • Triazolam • Zapizolam

Imidazobenzodiazepines	Bretazenil • Climazolam • Flumazenil • Imidazenil • Loprazolam • Midazolam • Ro15-4513 • Ro48-6791 • Sarmazenil • L-655,708

Oxazolobenzodiazepines	Cloxazolam • Flutazolam • Haloxazolam • Mexazolam • Oxazolam

Thienobenzodiazepines	Brotizolam • Ciclotizolam • Clotiazepam • Etizolam

Pyrazolodiazepinones	Ripazepam • Zolazepam

Benzodiazepine Prodrugs	Avizafone • Rilmazafone

Others	Bentazepam • Devazepide • GV-150,013 • Ketazolam • Razobazam • Premazepam • Tifluadom

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