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Coagulopathy

 
Medical Dictionary: co·ag·u·lop·a·thy
 
(kō-ăg'yə-lŏp'ə-thē)
n.

A disease affecting the coagulability of the blood.

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Veterinary Dictionary: coagulopathy
 

Any disorder of blood coagulation. See also hemophilia.

  • consumption c. — a bleeding tendency due to a reduction in clotting factors caused by their utilization. See also disseminated intravascular coagulation.
  • disseminated intravascular c. (DIC) — see disseminated intravascular coagulation.
  • hepatic c. — impaired synthesis of most clotting factors, including factors I, II, V, VII, IX and X, as well as other substances involved in the fibrinolytic system, in severe liver disease can cause significant abnormalities in coagulation.
 
Wikipedia: Coagulopathy
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Coagulopathy
Classification and external resources
ICD-10 D65.-D68.
ICD-9 286
DiseasesDB 29158
MeSH D001778

Coagulopathy, clotting disorder, and bleeding disorder, are a medical terms for a defect in the body's mechanism for blood clotting.

Contents

Causes

While there are several possible causes they generally result in excessive bleeding and a lack of clotting.

Acquired

Acquired causes of coagulopathy include anticoagulation with warfarin, liver failure, and disseminated intravascular coagulation. Additionally, the haemotoxic venom from certain species of snakes can cause this condition e.g. Bothrops, rattlesnakes and other species of viper.

Autoimmune causes of acquired coagulation disorders

There are autoimmune causes of coagulation disorders. They include acquired antibodies to coagulation factors; termed inhibitors of coagulation. The main inhibitor is directed against Factor VIII Another example is antiphospholipid syndrome.

Genetic

Some people lack the genes which typically produce protein coagulation factors which allow normal clotting. Various types of Hemophilia and von Willebrand disease are the major genetic disorders associated with coagulopathy.

See also



 
 
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consumption
hemostatic
disseminated intravascular coagulation

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Copyrights:

Medical Dictionary. The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company Read more
Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved.  Read more
Wikipedia. This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Coagulopathy" Read more