Costello syndrome is an exceedingly rare genetics syndrome first reported in 1977 by Dr. Jack Costello,a geneticist in New Zealand. With an estimated 300 people in the world, the incidence is 1:24 million, or fewer than 10 babies born with the syndrome per year worldwide. Researchers have recently identified Costello syndrome associated with mutations on the HRAS gene. for more information please visit http://costellokids.com