(medicine) A severe, often fatal condition that follows a severe crushing injury, particularly involving large muscle masses, characterized by fluid and blood loss, shock, hematuria, and renal failure. Also known as compression syndrome.
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McGraw-Hill Science & Technology Dictionary:
crush syndrome |
(medicine) A severe, often fatal condition that follows a severe crushing injury, particularly involving large muscle masses, characterized by fluid and blood loss, shock, hematuria, and renal failure. Also known as compression syndrome.
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Oxford Dictionary of Sports Science & Medicine:
compression syndrome |
An overuse injury characterized by pain and muscle stiffness in areas where the space available for tissues (e.g. muscles, nerves, and blood vessels) is limited. During exercise, the tissue is pressed against another structure and becomes inflamed or damaged. See also compartment syndrome, compression neuropathy.
American Heritage Stedman's Medical Dictionary:
crush syndrome |
A severe shocklike condition that follows release of a limb or other large body part after a prolonged period of compression, characterized by edema, hematuria, and renal failure. Also called compression syndrome.
Saunders Veterinary Dictionary:
crush syndrome |
The edema, oliguria and other clinical signs of renal failure that follow crushing of a part, especially a large muscle mass, causing the release of myoglobin. See also lower nephron nephrosis.
Wikipedia on Answers.com:
Crush syndrome |
| Crush syndrome | |
|---|---|
| Classification and external resources | |
| ICD-10 | T79.5 |
| ICD-9 | 958.5 |
| DiseasesDB | 13135 |
| MeSH | D003444 |
Crush syndrome (also traumatic rhabdomyolysis or Bywaters' syndrome) is a medical condition characterized by major shock and renal failure after a crushing injury to skeletal muscle. Cases occur commonly in catastrophes such as earthquakes, in which victims that have been trapped under fallen masonry.
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The syndrome was discovered by British physician Eric Bywaters in patients during the 1941 London Blitz.[1][2] It is a reperfusion injury that appears after the release of the crushing pressure. The mechanism is believed to be the release into the bloodstream of muscle breakdown products—notably myoglobin, potassium and phosphorus—that are the products of rhabdomyolysis (the breakdown of skeletal muscle damaged by ischemic conditions).
The specific action on the kidneys is not understood completely, but may be due partly to nephrotoxic metabolites of myoglobin.
Seigo Minami, a Japanese physician, first reported the crush syndrome in 1923.[3][4][5] He studied the pathology of three soldiers who died in World War I from insufficiency of the kidney. The renal changes were due to methohemoglobin infarction, resulting from the destruction of muscles, which is also seen in persons who are buried alive. The progressive acute renal failure is because of acute tubular necrosis.
Due to the risk of crush syndrome, current recommendation to lay first-aiders (in the UK) is to not release victims of crush injury who have been trapped for more than 15 minutes. Treatment consists of not releasing the tourniquet and fluid overloading the patient with added Dextran 4000 iu and slow release of pressure. If pressure is released during first aid then fluid is restricted and an input-output chart for the patient is maintained, and proteins are decreased in the diet.
The Australian Resuscitation Council recommended in March 2001 that first-aiders in Australia, where safe to do so, release the crushing pressure as soon as possible, avoid using a tourniquet and continually monitor the vital signs of the patient.[6] St John Ambulance Australia First Responders are trained in the same manner.
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![]() | McGraw-Hill Science & Technology Dictionary. McGraw-Hill Dictionary of Scientific and Technical Terms. Copyright © 2003, 1994, 1989, 1984, 1978, 1976, 1974 by McGraw-Hill Companies, Inc. All rights reserved. Read more |
![]() | Oxford Dictionary of Sports Science & Medicine. The Oxford Dictionary of Sports Science & Medicine. Copyright © Michael Kent 1998, 2006, 2007. All rights reserved. Read more | |
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![]() | American Heritage Stedman's Medical Dictionary. The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Read more |
![]() | Saunders Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved. Read more | |
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