Cryoglobulin is an abnormal blood protein associated with
several diseases.
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The test is done on a person's serum (the yellow liquid part of
blood that separates from the cells after the blood clots ).
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people with cryoglobulin to have symptoms during cold weather:
blanching, numbness, and pain in their fingers or toes (Raynaud's
phenomenon); bleeding into the skin (purpura); and pain in joints
(arthralgia).