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CTP synthase
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| Identifiers | |
| Symbol | CTPS |
| Entrez | 1503 |
| HUGO | 2519 |
| OMIM | 123860 |
| PDB | 1s1m |
| RefSeq | NM_001905 |
| UniProt | P17812 |
| Other data | |
| EC number | 6.3.4.2 |
| Locus | Chr. 1 p34.1 |
CTP synthase (or CTP synthetase) is an enzyme involved in pyrimidine biosynthesis.
It intraconverts UTP and CTP. The source of the amine/amino group in CTP is glutamine.
CTP synthase is activated by GTP, a purine. This acts to balance the relative amounts of purine and pyrimidine nucleotides.
CTP synthase is inhibited by CTP.
 CTP (Note nitrogen in upper right. Ignore rotation.) |
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