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Cyclopentolate

 
Drug Info: Cyclopentolate

Brand names: AK-Pentolate®, Cyclogyl®, Ocu-Pentolate®

Chemical formula:



Cyclopentolate eye solution

What is cyclopentolate eye solution?

CYCLOPENTOLATE (Cyclogyl®) causes the pupils in your eyes to widen, so they won't respond to light. The solution is normally used for diagnostic procedures. Cyclopentolate generic eye solution is available.

What should I tell my health care provider before I take this medicine?

They need to know if you have, or have had, any of these conditions:
• Down's Syndrome
• glaucoma
• kidney disease
• liver disease
• wear contact lenses
• an unusual or allergic reaction to cyclopentolate or other medications, foods, dyes or preservatives
• pregnant or trying to become pregnant
• breast-feeding

How should I use this medicine?

Cyclopentolate solution is for use only in the eye(s). Do not take by mouth. If used for other than diagnostic procedures, follow the directions on the prescription label. Wash hands before and after use. Tilt the head back slightly and pull the lower eyelid down with the index finger to form a pouch. Squeeze a single drop into the pouch and close your eyes. Apply gentle pressure to the inside corner of your eye for 1—3 minutes. If you are using more than one drop, repeat this process with 5 minutes between the drops. Do not touch dropper tip to any surface to prevent contamination. If more than one topical ophthalmic drug product is being used, the drugs should be administered at least 5 minutes apart. Use your doses at regular intervals. Do not use more often than prescribed.

If you wear contact lenses, remove them prior to using cyclopentolate. Contact lenses may be reinserted 15 minutes following application of cyclopentolate to the eye.

Feeding intolerance may occur. Infant feedings should be held for 4 hours following administration. Observe infants closely for at least 30 minutes following instillation of cyclopentolate.

Contact your pediatrician or health care professional regarding the use of this medication in children. Special care is needed.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for the next dose, use only that dose. Do not double doses.

What drug(s) may interact with cyclopentolate?

Cyclopentolate may decrease the effectiveness of the following eye medications:
• carbachol (Carbastat®, Carboptic®, Isopto Carbachol®, and Miostat®)
• cholinesterase inhibitors (physostigmine or Isopto® Eserine)
• pilocarpine (Isopto Carpine®, Pilocar®, E-Pilo®)

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking cyclopentolate?

If you wear contact lenses, be sure to remove them before placing drops in the eye. Certain chemicals in the solution can be absorbed by contact lenses.

Watch for drowsiness or dizziness that might interfere with driving or hazardous activities.

Visit your prescriber or health care professional for regular checks on your progress. Report any serious side effects promptly. Stop using cyclopentolate if your eyes become inflamed, painful or have a discharge, and see your prescriber or health care professional immediately.

Be careful not to touch the tip of the dispensing container onto the eye, or any other surface. Serious eye infections can result from contamination of eye solution.

If you are using other eye preparations, there should be an interval of at least 5 minutes between the use of cyclopentolate and the other eye preparation.

Wear dark glasses if cyclopentolate makes your eyes more sensitive to light.

What side effects may I notice from using cyclopentolate?

Side effects that you should report to your prescriber or health care professional as soon as possible:
• an allergic type reaction (skin rash, itching, hives)
• conjunctivitis or "pink eye"
• fast or irregular heartbeat
• hallucinations (seeing or hearing things that are not real), especially in children
• inflamed, swollen, painful, or infected eyes or eyelids
• swollen or bloated stomach (in infants)

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
• blurred vision
• burning, stinging, itching, or minor discomfort of the eyes or eyelids
• dry eyes
• dry mouth
• increased sensitivity to sunlight
• stinging
• swollen eyelids

Where can I keep my medicine?

Store cyclopentolate in the original bottle at room temperature up to 25 degrees C (77 degrees F). Keep the bottle tightly closed.


Last updated: 7/1/2002

Important Disclaimer: The drug information provided here is for educational purposes only. It is intended to supplement, not substitute for, the diagnosis, treatment and advice of a medical professional. This drug information does not cover all possible uses, precautions, side effects and interactions. It should not be construed to indicate that this or any drug is safe for you. Consult your medical professional for guidance before using any prescription or over the counter drugs.

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Wikipedia: Cyclopentolate
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Cyclopentolate
Systematic (IUPAC) name
2-(dimethylamino)ethyl (1-hydroxycyclopentyl)(phenyl)acetate
Identifiers
CAS number 512-15-2
ATC code S01FA04
PubChem 2905
Chemical data
Formula C17H25NO3 
Mol. mass 291.385 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

C

Legal status
Routes Topic
 Yes check.svgY(what is this?)  (verify)

Cyclopentolate is a mydriatic and cycloplegic agent commonly used during pediatric eye examinations. Cyclopentolate is also administered as an atropine substitute to reverse muscarinic and CNS effects of indirect cholinomimetic (anti-AChase) administration.

When used in eye drops in pediatric eye examinations, Cyclopentolate 0.5% and 1.0% is used to stop the eye focusing at near distance, enabling the optometrist or ophthalmologist to obtain a more accurate reading of the focusing power of the eyes.

The drops take around 30 minutes to work and around 24 hours to wear off (with patients advised not to drive a vehicle or operate machinery for the first 12 hours). The pupils become wider when Cyclopentolate is administered, making the eyes more sensitive to light. Close objects (and possibly distant objects) will also appear blurred.

Side effects to Cyclopentolate are rare, but can include effects such as disorientation, incoherent speech or visual disturbances during the 24-hour period that the drug has an effect.



 
 
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