Cyclopyrrolones are a family of hypnotic and anxiolytic nonbenzodiazepine drugs with similar pharmacological profiles to the benzodiazepine derivatives.
Although cyclopyrrolones are chemically unrelated to benzodiazepines, they function via the benzodiazepine receptor/GABA neurotransmitter. The best known cyclopyrrolone derivatives are zopiclone (Imovane) and its enantiomer eszopiclone (Lunesta), which are used to treat insomnia, and have a known potential for abuse. Other cyclopyrrolone derivatives include suriclone, pagoclone, pazinaclone and suproclone.
- Cyclopyrrolones
- eszopiclone - hypnotic (Lunesta)
- zopiclone - hypnotic (Imovane)
- pagoclone - anxiolytic
- suriclone - anxiolytic
- pazinaclone - anxiolytic
- suproclone - anxiolytic
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