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CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4

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CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4

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inhibitor

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CYP1A2 and CYP3A4 but I would like more indepth info too

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Yes, they both do. Its purpose is to oxidize small foreign organic molecules (xenobiotics), such as toxins or drugs, so that they can be removed from the body.

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With regard to pharmacokinetics, methadone is primarily metabolized by the CYP3A4 enzyme and to a lesser degree by CYP2B6. Medications that induce or inhibit this enzyme(which Lidocaine is one) can increase or decrease the serum concentrations of methadone.

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