In evolutionary developmental biology, the concept of deep homology is used to describe cases where growth and differentiation processes are governed by genetic mechanisms that are homologous and deeply conserved across a wide range of species.
Textbook examples common to metazoa include the homeotic genes that control differentiation along major body axes, and pax genes (especially PAX6) involved in the development of the eye and other sensory organs.
References
- Shubin N, Tabin C, Carroll S (August 1997). "Fossils, genes and the evolution of animal limbs". Nature 388 (6643): 639–48. doi:. PMID 9262397.
See also
External links
- Gilbert, Scott F. (2000). "Homologous Pathways of Development". Developmental biology (6th ed.). Sunderland, Mass: Sinauer Associates. ISBN 0-87893-243-7. http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=dbio&part=A5439.
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