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Delorazepam
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| Systematic (IUPAC) name | |
| (7-Chloro-5-(o-chlorophenyl) -1,3-dihydro-2H-1,4-benzodiazepin-2-one) | |
| Identifiers | |
| CAS number | 2894-67-9 |
| ATC code | none |
| PubChem | 17925 |
| DrugBank | ? |
| Chemical data | |
| Formula | C15H10Cl2N2O |
| Mol. mass | 304.02 |
| Pharmacokinetic data | |
| Bioavailability | 87% |
| Metabolism | Hepatic |
| Half life | [60-140] |
| Excretion | Renal |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status |
? |
| Routes | Oral
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Delorazepam also known as chlordesmethyldiazepam is a drug which is a benzodiazepine derivative. Its mainly used in Italy, where it is available under the trade name EN and Dadumir.
The potency of delorazepam is very high, and probably 1 mg delorazepam equals 10 mg diazepam.
In adults the half life is 99.7 (±22.3) hours for cpr and 96.9 (±19.7) hours for drops after a single dose of 1 mg. In children the half life is about 40 hours for children of 7 months, 27 hours for children between 2 and 3 years, 34 hours for more than 3 years.
Total clearance after single administration of 2 mg is 0.11 ml/min/kg.
See also
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