Desonide

Desonide
Systematic (IUPAC) name
(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
Identifiers
CAS number	638-94-8
ATC code	S01BA11
PubChem	12536
DrugBank	DB01260
Chemical data
Formula	C24H32O6
Mol. mass	416.507
Synonyms	(11β,16α)-11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?
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Desonide is the generic name of a low potency topical corticosteroid that has been available since the 1970s. It is primarily used to treat atopic dermatitis (eczema), seborrheic dermatitis, psoriasis and contact dermatitis in both adults and children and has a fairly good safety profile^[1] and is available as a cream, ointment, lotion, and, since September 19, 2006, as a foam under the tradename Verdeso Foam.

References

1. ^ Wong, Vicky Kwan; Brian Fuchs, Mark Lebwohl. "Overview on desonide 0.05%: a clinical safety profile". Journal of Drugs in Dermatology: JDD 3 (4): 393–7. doi:15303783. 

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