diethylstilbestrol

n.
A synthetic nonsteroidal substance, C₁₈H₂₀O₂, having estrogenic properties and used in the treatment of prostatic cancer. It was once used to treat menstrual disorders and to prevent miscarriage but is no longer prescribed for these cases because of the occurrence of reproductive abnormalities and cancers in the offspring of women so treated.

(dī-eth′ilstilbes′trôl)
n

An estrogenic substance, C₁₈H₂₀O₂, that has an estrogenic activity considered to be greater than that of estrone. Useful in treating menopausal symptoms and occasionally used in the therapy of chronic desquamative gingivitis associated with artificial or natural menopause.

Brand names: Stilphostrol®

Chemical formula:

Last updated: 7/1/2002

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A synthetic nonsteroidal estrogen; abbreviated DES. In cattle used to treat infertility and as a stimulant to weight gain by increasing muscular development. Its use is limited as a weight gain stimulant because of the possible entry of the compound into the human food chain. Excessive, long-term administration causes anal prolapse, abortion, fracture of the pelvis and nymphomaniac behavior. Sometimes used in dogs to treat misalliance and urinary incontinence, but limited by its myelotoxic effects.