| Dipalmitoylphosphatidylcholine | |
|---|---|
| Identifiers | |
| CAS number | 2644-64-6 |
| PubChem | 6138 |
| Properties | |
| Molecular formula | C40H80NO8P |
| Molar mass | 734.039 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Dipalmitoylphosphatidylcholine (DPPC) is a phospholipid and the major constituent of pulmonary surfactant. It is also the only surface active component of lung surfactant capable of lowering surface pressure to near zero levels. DPPC is synthesized mainly through remodeling of phosphatidylcholine. It is thought that a lysophosphatidylcholine (lysoPC) acyltransferase may play a critical role in its synthesis. The identity of this acyltransferase has not yet been confirmed.[1]
It is also used for research purposes in studying liposomes, lipid bilayers, and model biological membranes and in the formation of reconstituted HDL (rHDL) particles.
See also
References
- ^ Chen, Xueni (2006). "Identification and characterization of a lysophosphatidylcholine acyltransferase in alveolar type II cells". Proc Natl Acad Sci U S A 103 (31): 11724–11729. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1544237.
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