DRM is an initialism and may refer to:
Information technology
- Digital rights management, technologies which provide access control for digital media
- Data Reference Model, US federal guidelines for computer data standards
- Data Resource Management
- Digital Radio Mondiale, a digital radio broadcasting standard
- Direct Rendering Manager, a component of the Unix/Linux direct rendering infrastructure
- Distributed Resource Manager, software used to schedule batch jobs
- Dynamic Rich Media, a term used by Linkshare for their dynamic advertising
- Data Relationship Management, a.k.a Metadata Management, it is one of the Hyperion Application which is used for Planning
Medicine and psychology
- Deese-Roediger-McDermott-Paradigm, a paradigm in cognitive psychology for investigating false memories
- Desmin Related Myopathy, a rare neuromuscular disease
Biology
- Detergent Resistant Membranes
- Digestive Rate Model (Optimal Foraging)
Codes
- DRM, the IATA airport designator of Drama Airport in Drama, Greece
- DRM, the ICAO airline designator of Airways Flight Training, United Kingdom
Miscellaneous
- DRM (Japanese band), a J-pop girl group formerly known as Dream
- Design reference mission, a NASA term for a reference space architecture design
- Detrital Remanent Magnetization, the residual magnetization in sediments
- Deutsche Rennsport Meisterschaft, a 1970s German auto racing series
- Direct response marketing, a marketing tactic to elicit a direct consumer response
- Direct revelation mechanism in contract theory and mechanism design
- Direction du Renseignement Militaire, the Directorate of Military Intelligence of France
- Disability rights movement
- Gremlin (protein), the Xenopus homologue of DRM (rats)
- Disaster Risk Management (DRM) Programme, a UNDP project for supporting improvements in risk indentification
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