Elvucitabine: Information from Answers.com


Elvucitabine
Systematic (IUPAC) name
4-Amino-5-fluoro-1-[(2S,5R)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimidin-2-one
Identifiers
CAS number	181785-84-2
ATC code	none
PubChem	469717
Chemical data
Formula	C₉H₁₀F N₃O₃
Mol. mass	227.19 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Elvucitabine is an experimental nucleoside reverse transcriptase inhibitor (NRTI), developed by Achillion Pharmaceuticals, Inc. for the treatment of HIV.

Currently, it is in Phase II clinical trials.^[1]

References

This pharmacology-related article is a stub. You can help Wikipedia by expanding it.

gp41 (Enfuvirtide) · CCR5 (Maraviroc, Vicriviroc^†, PRO 140^†) · CD4 (Ibalizumab^†)

Nucleoside & Nucleotide (NRTI)	Nucleoside analogues/NARTIs: Abacavir (ABC)°^# · Emtricitabine (FTC)°^# · Lamivudine (3TC)°^# · Didanosine (ddI)^# · Zidovudine (AZT)^# · Apricitabine^† · Stampidine^† · Elvucitabine^† · Racivir^† · Amdoxovir^† · Stavudine (d4T)^# · Zalcitabine (ddC)^◊ Nucleotide analogues/NtRTIs: Tenofovir°^#

Non-Nucleoside (NNRTI)	Efavirenz°^# · Nevirapine^# · diarylpyrimidines (Etravirine, Rilpivirine^†) · Loviride^◊ · Delavirdine^◊ ·

Combined formulations

Experimental agents

Uncoating inhibitors	TRIM5alpha (gene)

Transcription inhibitors	Tat antagonists

Translation inhibitors	Trichosanthin

Other	Abzyme · Calanolide A · Ceragenin · Cyanovirin-N · Diarylpyrimidines · Epigallocatechin gallate (EGCG) · Foscarnet · Griffithsin · Hydroxyurea · Miltefosine · Portmanteau inhibitors · Seliciclib^† · Synergistic enhancers · Tre recombinase · Zinc finger protein transcription factor · KP-1461^†

Failed agents	Dexelvucitabine · Capravirine · Emivirine · Lodenosine · Atevirdine · Brecanavir · Aplaviroc

^#WHO-EM. ^†Undergoing clinical trials, not FDA approved. ^‡Withdrawn from market. ^§Development halted.
°DHHS preferred first-line agent. ^◊Formerly or rarely used agent.

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