Enprostil is a synthetic prostaglandin designed to resemble dinoprostone.
It is classified by the World Health Organization under "A02B: Drugs for peptic ulcer and gastro-oesophageal reflux disease."
External links
- Toshina K, Hirata I, Maemura K, Sasaki S, Murano M, Nitta M, Yamauchi H, Nishikawa T, Hamamoto N, Katsu K (2000). "Enprostil, a prostaglandin-E(2) analogue, inhibits interleukin-8 production of human colonic epithelial cell lines.". Scand J Immunol 52 (6): 570–5. doi:10.1046/j.1365-3083.2000.00815.x. PMID 11119262.
- Tari A, Hamada M, Kamiyasu T, Sumii K, Haruma K, Inoue M, Kishimoto S, Kajiyama G, Walsh J (1997). "Effect of enprostil on omeprazole-induced hypergastrinemia and inhibition of gastric acid secretion in peptic ulcer patients.". Dig Dis Sci 42 (8): 1741–6. doi:10.1023/A:1018825902055. PMID 9286243.
- Ching C, Lam S (1995). "A comparison of two prostaglandin analogues (enprostil vs misoprostol) in the treatment of acute duodenal ulcer disease.". J Gastroenterol 30 (5): 607–14. doi:10.1007/BF02367786. PMID 8574332.
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Autacoids, unsaturated fatty acids: Eicosanoids |
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| Prostanoids |
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| Leukotrienes (LT) |
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| Nonclassic |
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bronchoconstriction ( PGF2α, TXA2, LTC4, LTD4, LTE4)
vasoconstriction (PGF2α, TXA2, TXB2) · vasodilation (PGE2, PGI2, LTC4, LTD4, LTE4)
platelets: induce (TXA2) inhibit (PGD2, PGI2) · leukocytes: induce (TXA2, LTB4) inhibit (PGD2, PGE2)
labor stimulation: ( PGE2 (Dinoprostone), PGF2α (Dinoprost))
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