EOC may refer to:
- Earth Observation Center
- Economy of Communion in Freedom
- Economy of the Occupation, a series of publications
- Elswick Ordnance Company, a British armaments and ammunition manufacturer of the late 19th - early 20th century
- Engines of Creation (book), a molecular nanotechnology book by K. Eric Drexler
- Engine Off Coasting, a technique to reduce vehicle fuel consumption
- Equal Opportunities Commission, a former public body in the United Kingdom
- Emergency operations center, a type of command and control facility
- European Olympic Committees, an umbrella organisation of National Olympic Committees
- English-Ordered Chinese, a tool to teach beginner's English
- Ethernet over coax, a family of transmission technologies
- Evangelical Orthodox Church, an Eastern Orthodox Christian movement
- End of Course Examination, see End of Course Test
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