epidermolysis

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(medicine) The easy separation of various layers of skin, primarily of the epidermis from the corium, observed in certain pathological conditions.

A condition in which the epidermis is loosely attached to the dermis and readily detaches or forms blisters.

A loosened state of the epidermis with formation of blebs and bullae either spontaneously or at the site of trauma.

• e. bullosa — a hereditary disease of humans, Collie dogs, Shetland sheepdogs, Suffolk, South Dorset Down and Scottish blackface sheep, and Simmental and Brangus calves. Characterized by epidermal bullae, particularly on areas of pressure or trauma and in sheep in the mouth and on woolless skin. There may be shedding of hooves and horns. Called also red foot disease.
• congenital bovine e. — ulcers on lips, gums, tongue, muzzle and limb extremities at birth; skin lesions may be local alopecia without ulceration; resembles epidermolysus bullosa simplex in humans; an autosomal dominant recorded in Simmentals.