extirpation

[L. extirpatio, exstirpatio: cf. F. extirpation.]
The act of extirpating or rooting out, or the state of being extirpated; eradication; excision; total destruction; as, the extirpation of weeds from land, of evil from the heart, of a race of men, of heresy.

noun

Utter destruction: annihilation, eradication, extermination, extinction, extinguishment, liquidation, obliteration. See crimes, help/harm/harmless, make/unmake.

The surgical removal of an organ, a part of an organ, or a diseased tissue.

The noun has 2 meanings:

Meaning #1: surgical removal of a body part or tissue
  Synonyms: ablation, cutting out, excision

Meaning #2: the act of pulling up or out; uprooting; cutting off from existence
  Synonyms: excision, deracination