Extramedullary hematopoiesis refers to hematopoiesis occurring outside of the medulla of the bone.
In some cases, it may be physiologic. For example, during fetal development, hematopoiesis occurs at many different locations, such as the liver.[1]
However, it is more frequently associated with pathologic processes. For example, it can be caused by myelofibrosis.[2]
It can sometimes be identified via computed tomography.[3]
References
- ^ "hematopoiesis". http://www.ndsu.nodak.edu/instruct/tcolvill/435/hematopoiesis.htm. Retrieved 2009-02-25.
- ^ Chunduri S, Gaitonde S, Ciurea SO, Hoffman R, Rondelli D (October 2008). "Pulmonary extramedullary hematopoiesis in patients with myelofibrosis undergoing allogeneic stem cell transplantation". Haematologica 93 (10): 1593–5. doi:. PMID 18641018. http://www.haematologica.org/cgi/pmidlookup?view=long&pmid=18641018.
- ^ Marchiori E, Escuissato DL, Irion KL, et al. (October 2008). "Extramedullary hematopoiesis: findings on computed tomography scans of the chest in 6 patients". J Bras Pneumol 34 (10): 812–6. PMID 19009214. http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132008001000009&lng=en&nrm=iso&tlng=en.
See also
External links
- Berkmen YM, Zalta BA (December 2007). "Case 126: extramedullary hematopoiesis". Radiology 245 (3): 905–8. doi:. PMID 18024458. http://radiology.rsnajnls.org/cgi/pmidlookup?view=long&pmid=18024458.
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