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Formate kinase

 
Wikipedia: Formate kinase
formate kinase
Identifiers
EC number 2.7.2.6
CAS number 9026-65-7
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures
Gene Ontology AmiGO / EGO

In enzymology, a formate kinase (EC 2.7.2.6) is an enzyme that catalyzes the chemical reaction

ATP + formate \rightleftharpoons ADP + formyl phosphate

Thus, the two substrates of this enzyme are ATP and formate, whereas its two products are ADP and formyl phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a carboxy group as acceptor. The systematic name of this enzyme class is ATP:formate phosphotransferase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

References

  • Sly WS and Stadtman ER (1963). "Formate metabolism. II. Enzymatic synthesis of formyl phosphate and formyl coenzyme A in Clostridium cylindrosporum". J. Biol. Chem. 238: 2639–2647. 

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