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Fundic glands

 
Sci-Tech Dictionary: fundic gland
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(′fən·dik ′gland)

(anatomy) Any of the glands of the corpus and fundus of the stomach.

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Fundic glands
H&E stain of fundic gland polyp showing shortening of the gastric pits with cystic dilatation
Latin glandulae gastricae
Gray's subject #247 1166

The fundus glands (or fundic glands, or gastric glands) are found in the body and fundus of the stomach.

They are simple tubes, two or more of which open into a single duct.


Contents

Pathology

Fundic gland polyposis is a medical syndrome where the fundus of the stomach develops many polyps.

Types of cells

Location Name Description Secretion Staining
Isthmus goblet cells In gastric pits. mucus gel layer Clear
Neck parietal (oxyntic) cells Between the chief cells and the basement membrane, larger oval cells, which stain deeply with eosin, are found; these cells are studded throughout the tube at intervals, giving it a beaded or varicose appearance. These are known as the parietal cells or oxyntic cells, and they are connected with the lumen by fine channels which run into their substance. gastric acid and intrinsic factor Acidophilic
Base chief (zymogenic) cells At the point where they open into the duct, which is termed the neck, the epithelium alters, and consists of short columnar or polyhedral, granular cells, which almost fill the tube, so that the lumen becomes suddenly constricted and is continued down as a very fine channel. They are known as the chief cells or central cells of the glands. pepsinogen, rennin Basophilic
Base enteroendocrine (APUD) cells G cells are a type of enteroendocrine cell that secrete the hormone gastrin (gastrin promotes the secretion of pepsinogen (by chief cells) and HCl (by parietal cells) and promotes gastric contractions to mix contents). hormones -

Additional images

A fundus gland. A. Transverse section of gland.

Layers of stomach wall

External links

This article was originally based on an entry from a public domain edition of Gray's Anatomy. As such, some of the information contained herein may be outdated.

v • d • e
Anatomy of torso, digestive system: Gastrointestinal tract
Upper GI
To stomach
Lower GI
Termination


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Sci-Tech Dictionary. McGraw-Hill Dictionary of Scientific and Technical Terms. Copyright © 2003, 1994, 1989, 1984, 1978, 1976, 1974 by McGraw-Hill Companies, Inc. All rights reserved.  Read more
Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "Fundic glands".  Read more