3-Phosphoglyceric acid

3-Phosphoglyceric acid
IUPAC name	(2R)-2-Hydroxy-3-phosphonooxypropanoic acid
Identifiers
CAS number	[820-11-1]
PubChem	439183
SMILES	C([C@H](C(=O)O)O)OP(=O)(O)O
Properties
Molecular formula	C3H7O7P
Molar mass	186.06 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

3-Phosphoglyceric acid (3PG), or glycerate 3-phosphate (GP), is a biochemically significant 3-carbon molecule that is a metabolic intermediate in both glycolysis and the Calvin cycle. This chemical is often termed PGA when referring to the Calvin cycle. 3-Phosphoglycerate is the resultant of the split of 6 carbon intermediate that is so unstable it splits instantly. And two 3-phosphoglycerate is produced for each molecule of CO₂.

Glycolysis

1,3-bisphospho-D-glycerate	3-phosphoglycerate kinase		3-phospho-D-glycerate	Phosphoglyceromutase		2-phospho-D-glycerate
	ADP	ATP
	ADP	ATP
	3-phosphoglycerate kinase			Phosphoglyceromutase

Compound C00236 at KEGG Pathway Database. Enzyme 2.7.2.3 at KEGG Pathway Database. Compound C00197 at KEGG Pathway Database. Enzyme 5.4.2.1 at KEGG Pathway Database. Compound C00631 at KEGG Pathway Database.

Calvin cycle

In the Calvin cycle, two glycerate 3-phosphate molecules are reduced to form two molecules of glyceraldehyde 3-phosphate (PGAL). This is the first compound formed during the C3 or Calvin cycle. It is a reactive biomolecule which is easily reduced.

Amino acid synthesis

Glycerate 3-phosphate is also a precursor for serine, which in turn, can create cysteine and glycine through the homocysteine cycle.

See also

• 2-Phosphoglyceric acid

v • d • e Glycolysis Metabolic Pathway

Glucose Hexokinase Glucose 6-phosphate Glucose-6-phosphate isomerase Fructose 6-phosphate phosphofructokinase-1 Fructose 1,6-bisphosphate Fructose bisphosphate aldolase ATP ADP ATP ADP Dihydroxyacetone phosphate Glyceraldehyde 3-phosphate Triosephosphate isomerase Glyceraldehyde 3-phosphate Glyceraldehyde-3-phosphate dehydrogenase 1,3-Bisphosphoglycerate NAD+ + Pi NADH + H+ + 2 2 Phosphoglycerate kinase 3-Phosphoglycerate Phosphoglycerate mutase 2-Phosphoglycerate Phosphopyruvate hydratase(Enolase) Phosphoenolpyruvate Pyruvate kinase Pyruvate ADP ATP H2O ADP ATP 2 2 2 2 see also disorders

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