
[GLYCER(IN) + -IDE.]
Esters of glycerol with fatty acids. Since glycerol has three hydroxyl groups, it can be esterified with three molecules of fatty acid to form a triacylglycerol (sometimes known as a triglyceride), the main type of fat in the diet and body, sometimes known as simple fats or neutral fats. Mono- and diacylglycerols have respectively one and two fatty acids esterified to glycerol, with the remaining hydroxyl group (s) free.
| glyceric aldehyde, glycerate, glyceraldehyde-3-phosphate dehydrogenase | |
| glycero+, glycero-, glycerol |
An organic acid ester of glycerin, designated, according to the number of ester linkages, as a mono, di- or triglyceride.
An ester of glycerin with one or more aliphatic acids.
Glycerides, more correctly known as acylglycerols, are esters formed from glycerol and fatty acids.
Glycerol has three hydroxyl functional groups, which can be esterified with one, two, or three fatty acids to form monoglycerides, diglycerides, and triglycerides.
Vegetable oils and animal fats contain mostly triglycerides, but are broken down by natural enzymes (lipases) into mono and diglycerides and free fatty acids.
Soaps are formed from the reaction of glycerides with sodium hydroxide. The product of the reaction is glycerol and salts of fatty acids. Fatty acids in the soap emulsify the oils in dirt, enabling the removal of oily dirt with water.
Partial glycerides are esters of glycerol with fatty acids, where not all the hydroxyl groups are esterified. Since some of its hydroxyl groups are free the molecule is polar. Short chain partial glycerides are more highly polarized, and have excellent solvent properties for many hard-to-solubilize drugs.[1]
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