The term granular layer may refer to:
- the granular layer of Tomes, seen in dentin of the teeth. When dry section of the root dentin of teeth are visualized under transmitted light, a granular layer is seen adjacent to cementum.It is believed to be caused by coalescing & looping of terminal portion of dentinal tubules.
- The Granular layer (cerebellum) of the cortex of the human cerebellum
- The Granular layer (cerebral cortex) of the cerebral cortex
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