GNR may be:
In Music
- Guns N' Roses, a hard rock band from Hollywood, California in the United States.
- GNR, a Portuguese rock band.
Railways
- Great Northern Railway of Great Britain.
- Great Northern Railway of Ireland. (usually GNR(I))
- Great Northern Railway of the United States.
- Georgia Northeastern Railroad, in the U.S. state of Georgia.
Roads
- Great North Road (Africa)
- Great North Road (Australia)
- Great North Road (British Columbia)
- Great North Road (New Zealand)
- Great North Road (United Kingdom)
- Great North Road (Zambia)
Para military organizations
- Guarda Nacional Republicana of Portugal - Portuguese National Guard; Portuguese gendarmerie
- Guardia Nazionale Repubblicana of Italian Social Republic (1943-45). Replaced the MVSN and the Carabinieri military police corps.
Others
- In bioethics, GNR denotes the technologies of genetics, nanotechnology, and robotics.
- Global Name Registry, the operator of the .name top-level domain.
- Great North Radio, a radio station in North East England.
- "Giant Naked Rei", a nickname used by fans of the anime Neon Genesis Evangelion to describe the appearance of the angel Lilith in the series' final The End of Evangelion|cinematic installment
- Great North Run, an annual half-marathon held in Autumn between Newcastle upon Tyne and South Shields in England
- Gram negative rod in microbiology
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