Haloprogin

Haloprogin

Systematic (IUPAC) name
1,2,4-trichloro-5-[(3-iodoprop-2-yn-1-yl)oxy]benzene
Identifiers
CAS number	777-11-7
ATC code	D01AE11
PubChem	3561
DrugBank	APRD01011
Chemical data
Formula	C9H4Cl3IO
Mol. mass	361.39
Physical data
Melt. point	113.5 °C (236 °F)
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status	Not available in U.S.
Routes	Topical
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Haloprogin is an antifungal drug used to treat athlete's foot and other fungal infections. It is marketed in creams under the trade names Halotex, Mycanden, Mycilan, and Polik.

Action

Haloprogin was previously used in 1% topical creams as an antifungal agent. It was marketed over the counter primarily to treat tinea infections of the skin. The mechanism of action is unknown.^[1]

Haloprogin had a high incidence of side effects including: irritation, burning, vesiculation (blisters), scaling, and itching. It has since been discontinued due to the emergence of more modern antifungals with fewer side effects.^[2]

References

1. ^ "Haloprogin". Drugs@FDA. Food and Drug Administration. http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm?fuseaction=Search.Overview&DrugName=HALOTEX. Retrieved 2007-02-17. 
2. ^ "Haloprogin". DrugBank. University of Alberta. Nov 06, 2006. http://redpoll.pharmacy.ualberta.ca/drugbank/cgi-bin/getCard.cgi?CARD=APRD01011.txt. Retrieved 2007-02-17. 

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