| Haplogroup E |
| Time of origin |
approx. 30,000 YBP |
| Place of origin |
Northeast Sundaland or around Sulawesi and Sulu Seas[1] |
| Ancestor |
M9 |
| Descendants |
E1, E2 |
| Defining mutationsDescendants |
3027, 3705, 7598, 13626, 16390[2] |
In human mitochondrial genetics, Haplogroup E is a human mitochondrial DNA (mtDNA) haplogroup. It is a subgroup of Haplogroup M.
Origin
Distribution
Haplogroup E has a southern Asia distribution. Until now it has been detected in the Malay peninsula populations and in the Sabah of Borneo; and it is also present in coastal Papua New Guinea as well as in Taiwan, in the Philippines, and in some Pacific islands such as Guam.
Subclades
Tree
This phylogenetic tree of haplogroup E subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation[2] and subsequent published research.
See also
References
- ^ Soares et al. (2008), Climate Change and Postglacial Human Dispersals in Southeast Asia, Molecular Biology and Evolution, June 2008; 25: 1213
- ^ a b van Oven, Mannis; Manfred Kayser (13 Oct 2008). "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation". Human Mutation 30 (2): E386–E394. doi:10.1002/humu.20921. PMID 18853457 doi:10.1002/humu.20921. http://www3.interscience.wiley.com/journal/121449735/abstract?CRETRY=1&SRETRY=0. Retrieved 2009-05-20. |url=http://www3.interscience.wiley.com/journal/121449735/abstract?CRETRY=1|doi_brokendate=2009-07-06 }}
External links
- General
- Haplogroup E
- Ballinger, S.W., Schurr, T.G., Torroni, A., Gan, Y.Y., Hodge, J.A., Hassan, K., Chen, K.H., and Wallace, D.C. 1992. "Southeast Asian mitochondrial DNA analysis reveals genetic continuity of ancient mongoloid migrations". Genetics 130: 139-152.
- Herrnstadt, C., Elson, J.L., Fahy, E., Preston, G., Turnbull, D.M., Anderson, C., Ghosh, S.S., Olefsky, J.M., Beal, M.F., Davis, R.E., et al. 2002. "Reduced-median-network analysis of complete mitochondrial DNA coding-region sequences for the major African, Asian, and European haplogroups". American Journal of Human Genetics 70: 1152-1171.
- Ingman, M., Kaessmann, H., Pääbo, S., and Gyllensten, U. 2000. Mitochondrial genome variation and the origin of modern humans. Nature 408: 708-713.
- Stoneking, M., Jorde, L.B., Bhatia, K., and Wilson, A.C. 1990. Geographic variation in human mitochondrial DNA from Papua New Guinea. Genetics 124: 717-733.
- Trejaut, Jean A; Toomas Kivisild; Jun Hun Loo; Chien Liang Lee; Chun Lin He; Chia Jung Hsu; Zheng Yuan Li; and Marie Lin. 2005. Traces of Archaic Mitochondrial Lineages Persist in Austronesian-Speaking Formosan Populations Plos Biology 3 (8).
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