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Yes, although ABO and Rh are the main causes of haemolytic transfusion reactions (HTR's), if a person with an anti-K antibody is transfused with red blood cells which have a kell antigen on their surface, it has been known to cause delayed HTR's through the supression of erythropoiesis.

As for haemolytic disease of the newborn, it is thought that anti-K can cause HDN vie anaemia, not jaundice.

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Yes, although ABO and Rh are the main causes of haemolytic transfusion reactions (HTR's), if a person with an anti-K antibody is transfused with red blood cells which have a kell antigen on their surface, it has been known to cause delayed HTR's through the supression of erythropoiesis.

As for haemolytic disease of the newborn, it is thought that anti-K can cause HDN vie anaemia, not jaundice.

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Hemolytic disease of the newborn is known as erythroblastosis fetalis

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Apparently, the Kell blood group system is separate from the ABO and Rh blood groups. The Kell blood group can also trigger immune reactions.

According to nih.gov, "Antibodies that target Kell antigens can cause transfusion reactions and hemolytic disease of the newborn (HDN). In the case of HDN, ABO and Rh incompatibility are more common causes. However, disease caused by maternal anti-ABO tends to be mild, and disease caused by maternal anti-Rh can largely be prevented. The infrequent cases of HDN caused by Kell immunization tend to result in severe fetal anemia because maternal anti-Kell target fetal red blood cell (RBC) precursors, suppressing the fetal production of RBCs."

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Rh-induced hemolytic disease of the newborn

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A hemolytic disease of the newborn that is characterized by an increase in circulating red blood cells and by jaundice and that occurs when the system of an Rh-negative mother produces antibodies to an antigen in the blood of an Rh-positive fetus which cross the placenta and destroy fetal red blood cells, called also hemolytic disease of the newborn.

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