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Hepatitis Virus Tests: Abnormal results

 
Medical Encyclopedia: Hepatitis Virus Tests: Abnormal results
 
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Hepatitis A: A single positive anti-HAV test may indicate previous exposure to the virus, but due to the antibody persisting so long in the bloodstream, only evidence of a rising anti-HAV titer confirms hepatitis A. Determining recent infection rests on identifying the antibody as IgM (associated with recent infection). A negative anti-HAV test rules out hepatitis A.

Hepatitis B: High levels of HBsAg that continue for three or more months after onset of acute infection suggest development of chronic hepatitis or carrier status. Detection of anti-HBs signals late convalescence or recovery from infection. This antibody remains in the blood to provide immunity to reinfection.

Hepatitis C (non-A, non-B hepatitis): Anti-HBc develops after exposure to hepatitis B. As an early indicator of acute infection, antibody (IgM) to core antigen (anti-HBc IgM) is rarely detected in chronic infection, so it is useful in distinguishing acute from chronic infection, and hepatitis B from non-A, non-B.

— Janis O. Flores



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