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H1- 21.3kD

H2a - 14.3kD

H2b - 13.8kD

H3 - 15.0kD

H4 - 11.3kD

Q: What are the molecular weights of histone proteins?

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H1- 21.3kD

H2a - 14.3kD

H2b - 13.8kD

H3 - 15.0kD

H4 - 11.3kD

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Part of Chromatin. Smaller units made of DNA & histone octamers (8). 2 of each: H2A, H2B, H3, H4, all attached to the larger H1.

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Chromatin composed of tetramer of histones 2 copies each of Histone H2A, H2B, H3 and H4. DNA is bound on the nucleosome and uses 147 basepairs of DNA.

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what are the sources of histone binding protien RbAp48

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Since phosphate groups have a negative charge, adding them to histone tails neutralizes them and probably reduces their affinity for DNA. It might contribute to transcription because it stimulates histone acetyltransferases which cause histone acetylation and enhance transcription.

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