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Histoplasmosis: Treatment

 
Medical Encyclopedia: Histoplasmosis: Treatment

Acute primary histoplasmosis generally requires no treatment other than rest. Non-prescription drugs such as acetaminophen (Tylenol) may be used to treat pain and relieve fever. Avoiding smoke and using a cool air humidifier may ease chest pain.

Patients with an intact immune system who develop chronic histoplasmosis are treated with the drug ketoconazole (Nizoral) or amphotericin B (Fungizone). Patients with suppressed immune systems are treated with amphotericin B, which is given intravenously. Because of its potentially toxic side effects, hospitalization is often required. The patient may also receive other drugs to minimize the side effects of the amphotericin B.

Patients with AIDS must continue to take the drug itraconazole (Sporonox) orally for the rest of their lives in order to prevent a relapse. If the patient can not tolerate itraconazole, the drug fluconazole (Diflucan) can be substituted.

— Tish Davidson



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