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Hofbauer cell

 
Sci-Tech Dictionary: Hofbauer cell
(′hōf·bau̇r ′sel)

(histology) A large, possibly phagocytic cell found in chorionic villi.


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Hofbauer cells are oval cells found in the placenta, within the core of the chorionic villous. They are believed to be a type of macrophage[1][2] and are most likely involved in preventing the transmission of pathogens from the mother to the foetus (so-called vertical transmission).

Under histology sections, Hofbauer cells appeared with discernible amount of cytoplasm.

Notes

  1. ^ Wood GW. (1980) Mononuclear phagocytes in the human placenta. Placenta. 1(2):113-23
  2. ^ Zaccheo D. Pistoia V. Castellucci M. Martinoli C. (1989) Isolation and characterization of Hofbauer cells from human placental villi. Archives of Gynecology & Obstetrics. 246(4):189-200

 
 
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